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The world’s first insulin pump with
REAL-Time continuous
glucose monitoring
The new MiniMed Paradigm® REAL-Time System gives you a superb solution
to control your diabetes…with more freedom to live a healthier, better life. This
breakthrough technology combines a “smart” insulin pump with the new benefit
of REAL-Time continuous glucose monitoring. The system displays REAL-Time
glucose readings, trend graphs, and directional arrows—all day, all night—so you
can discover how your diet, exercise, medication, and lifestyle impact your
glucose levels. REAL-Time alarms are designed to protect you by warning you
of low and high glucose levels. Armed with these insights, you can take action
right away* to gain greater control of your glucose levels.1-5 That means you can
avoid having those dangerous low and high glucose levels. It’s another major
step towards an artificial pancreas from Medtronic Diabetes.
*A confirmatory fingerstick test is required prior to taking action.

Live between the lines
Now you can stay within your target range—between the lines—with greater control of your
glucose levels. The new MiniMed Paradigm® REAL-Time System displays updated glucose readings
every 5 minutes, 24 hours a day - up to 288 readings every day - to show you patterns and
problems that fingersticks may miss. Continuous glucose monitoring, compared to fi ngersticks
alone, is 4 times more effective in detecting dangerous lows and highs that require therapy
adjustments.2 Up to 60% of lows may not be recognised with just fingersticks.6,7 (See Figures 1 and
2.) Therapy based on continuous glucose monitoring has also been shown to reduce HbA1c levels
compared to fingersticks alone.1-3And REAL-Time alarms are designed to alert you of low and high
glucose levels, enabling you to avoid or reduce the duration of glycaemic excursions.

Greater freedom to live life your way
Thanks to insulin pump therapy and continuous glucose monitoring with the MiniMed Paradigm
REAL-Time System, you can eat, sleep, work, and exercise when you want.
You’re not locked
into a rigid regimen like you are with multiple daily injections.8 You can also enjoy the peace of
mind that comes with knowing that you have greater control of your diabetes—and that you can
get the information you need to take action and stop problems before they start. That’s why the
MiniMed Paradigm REAL-Time System may make a REAL difference in helping you live a healthier
life. And what could be more important than that?

REAL-Time displays keep you
in control with REAL confidence

Easy to use, easy to wear
The MiniMed Paradigm® 522 and 722 insulin pumps are really easy to fit into your
lifestyle. It’s comfortable, small, and discreet—about the size and weight of a mobile
phone—so you can wear it wherever you want. You can attach it to your belt, hide it in a
pocket, or just put it under your clothing.
A tiny glucose sensor monitors glucose levels for up to
3 days of continuous use. The sensor is very small and is
easily inserted—virtually painlessly—under the skin using
an auto-insertion device that comes with the system.
Once the needle is removed, all that remains is a
small sensor.
The glucose sensor is attached to a small, waterproof
transmitter that sends the glucose data wirelessly to
the MiniMed Paradigm 522 or 722 insulin pump. Since the
transmitter is not attached to the insulin pump, you have
considerable flexibility in placement of the components.
Insulin is delivered through an infusion set with a
tiny, soft plastic tube called a cannula. The cannula lies
comfortably just beneath the surface of your skin. You generally wear an infusion set for 2
to 3 days and then replace it.
The insulin pump delivers insulin according to your instructions. You set a basal rate -
a small, continuous dose of rapid-acting insulin that takes the place of long-acting insulin
delivered with an injection. You can program your basal rate at any time to accommodate
your different needs at different times of the day, making the insulin pump act more
like a healthy pancreas. You also instruct your insulin pump to deliver a bolus dose
whenever you need one—when you eat or to correct a high blood glucose.

Tools to make the MiniMed Paradigm® 522 or 722
insulin pump more effective
Bolus Wizard® Calculator: The patented Bolus Wizard
calculator performs the complicated bolus calculation for you,
reducing the likelihood of errors that lead to inappropriate
dosing. At the touch of a few buttons, the calculator uses
your personal settings, blood glucose readings, glucose target,
carbohydrate entry, and the amount of active insulin remaining
in your body to suggest an appropriate bolus amount.
Safety features for better protection
and control
With the MiniMed Paradigm 522 or 722 insulin pump, you
get more than 6 million safety checks to protect you all
day, every day. Built-in alerts protect you against a low
battery or reservoir. The ParadigmPAL™ software allows
you to set up, change, and save your insulin pump settings
on your personal computer so you always have a backup.
Options to fit your life and style
The MiniMed Paradigm® 522 or 722 insulin pump gives
you options: your choice of colors and a choice of
reservoir sizes—176 or 300 units. A remote control is
included for more privacy with one-touch bolus delivery.
A wide variety of infusion sets for every body type and
comprehensive accessories are also available to fit
your lifestyle needs. All MiniMed Paradigm insulin
pumps are water-resistant to protect them from
splashes or a temporary
dunk in water.


Comprehensive patient support
To get you started right—and help you along the way—Medtronic Diabetes
provides thorough insulin pump and continuous glucose monitoring training,
coupled with a 24-hour Product Helpline, 365 days a year.

For more information, talk to your healthcare provider,
call Medtronic Diabetes
on 1800 668 670 or email us
| 1. |
Bode BW, Gross TM, Thornton KR, Mastrototaro JJ. Continuous glucose monitoring used to adjust diabetes therapy improves glycosylated hemoglobin: a pilot study. Diabetes Res Clin Pract. 1999;46(3):183- 190. |
| 2. |
Kaufman FR, Gibson LC, Halvorson M, Carpenter S, Fisher LK, Pitukcheewanont P. A pilot study of the continuous glucose monitoring system: clinical decisions and glycaemic control after its use in pediatric type 1 diabetic subjects. Diabetes Care. 2001;24(12):2030-2034. |
| 3. |
Ludvigsson J, Hanas R. Continuous subcutaneous glucose monitoring improved metabolic control in pediatric patients with type 1 diabetes: a controlled crossover study. Pediatrics. 2003;111(5 pt 1):933-938. |
| 4. |
Doyle EA, Weinzimer SA, Steffen AT, Ahern JA, Vincent M, Tamborlane WV. A randomized, prospective trial comparing the effi cacy of continuous subcutaneous insulin infusion with multiple daily injections using insulin glargine. Diabetes Care. 2004;27(7):1554-1558. |
| 5. |
Bode B, Gross K, Rikalo N, et al. Alarms based on real-time sensor glucose values alert patients to hypo- and hyperglycemia: the guardian continuous monitoring system. Diabetes Technol Ther. 2004;6(2):105-113. |
| 6. |
Gross TM, Mastrototaro JJ. Effi cacy and reliability of the continuous glucose monitoring system. Diabetes Technol Ther. 2000;2(suppl 1):S19-S26. |
| 7. |
Skyler JS. The economic burden of diabetes and the benefi ts of improved glycaemic control: the potential role of a continuous glucose monitoring system. Diabetes Technol Ther. 2000;2(suppl 1):S7-S12. |
| 8. |
Bode BW, Tamborlane WV, Davidson PC. Insulin pump therapy in the 21st century. Strategies for successful use in adults, adolescents, and children with diabetes. Postgrad Med. 2002;111(5):69-77. |
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